Understanding atmospheric pollution requires the quantification of the various processes which govern the evolution of chemical species in the gas and particle phases in the lower atmosphere before taking them into account in 3D models. The objective of LISA in this field is  to provide predictions and spatial descriptions of the various pollutants from the urban to the continental scale. In addition, the impact of pollution on the time evolution of the materials of the built heritage is studied. For these purposes, in situ and satellite observations, numerical modeling, as well as experimental laboratory simulations, are simultaneously set-up.